Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531647 | 0.97 | ALDH1A1 (0.47) | ALDH1A1MYCHPGDLMNAPOLB | |
| SCHEMBL10330247 | 0.82 | HPGD (0.56) | ALDH1A1MYCHPGDLMNAPOLB | |
| SCHEMBL12442637 | 0.80 | HPGD (0.62) | ALDH1A1MYCHPGDLMNAPOLB | |
| SCHEMBL29944223 | 0.80 | HPGD (0.62) | ALDH1A1MYCHPGDLMNAPOLB | |
| SCHEMBL13779974 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MYCHPGDLMNAPOLB | |
| Ethylene SCHEMBL8381698 | 0.78 | GAA (0.58) | ALDH1A1HPGDPOLB | |
| SCHEMBL2219100 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1MYCHPGDMAPTHTT | |
| SCHEMBL2733860 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MYCHPGDLMNAPOLB | |
| SCHEMBL18390537 | 0.75 | HRH3 (0.62) | ALDH1A1MYCHPGDTDP1HRH3 | |
| SCHEMBL18390522 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MYCHPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |