Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 10/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL6111434 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Hexane SCHEMBL77892 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Hexane SCHEMBL9340228 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL21899639 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Hexane SCHEMBL534288 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL14208157 | 0.97 | LMNA (0.52) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL6354364 | 0.97 | LMNA (0.52) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL2344964 | 0.97 | LMNA (0.52) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL2350132 | 0.95 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL2348904 | 0.95 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874436-A | EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS | DEMERS JAMES P (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1997048676-A1 | TRIPHENYLALKYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5643950-A | INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |