Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517281 | 0.90 | GRM2 (0.35) | GRIN2BGRM2PDGFRBPDGFRAACACB | |
| SCHEMBL9311774 | 0.90 | ACACB (0.32) | PDGFRBPDGFRAACACB | |
| SCHEMBL8517439 | 0.87 | NPC1 (0.45) | GRIN2BGRM2CACNA1H | |
| SCHEMBL9311961 | 0.86 | GRIN2B (0.33) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL9311965 | 0.86 | GRIN2B (0.33) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL9311955 | 0.86 | GRIN2B (0.33) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL9311947 | 0.86 | GRIN2B (0.33) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL9646838 | 0.86 | GRIN2B (0.34) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL9646834 | 0.86 | GRIN2B (0.34) | NPY5RGRIN2BGRM2PDGFRBPDGFRA | |
| SCHEMBL8517255 | 0.85 | LMNA (0.36) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |