Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247940 | 0.83 | DHODH (0.49) | HTR2ATRPM4ALDH1A1HSD17B10HIF1A | |
| SCHEMBL7360085 | 0.79 | CHEK1 (0.55) | HTR2ATRPM4ALDH1A1HSD17B10HIF1A | |
| SCHEMBL615452 | 0.79 | TRPM4 (0.54) | HTR2ATRPM4ALDH1A1HSD17B10HIF1A | |
| SCHEMBL133410 | 0.78 | HPRT1 (0.58) | HTR2AALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL29729625 | 0.78 | HPRT1 (0.58) | HTR2AALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL27900087 | 0.78 | HTR2A (0.52) | HTR2AALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL15379970 | 0.78 | HTR2A (0.52) | HTR2AALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL8655955 | 0.78 | HTR2A (0.52) | HTR2AALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL20961847 | 0.78 | HTR2A (0.48) | HTR2AALDH1A1HSD17B10HIF1ALOXL2 | |
| SCHEMBL18138405 | 0.77 | TRPM4 (0.46) | HTR2ATRPM4ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9412955-B2 | Fluorescent isoindoline dyes | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | UNIV SOUTHERN CALIFORNIA (US) | 2015-11-05 | — | — | US | disclosed |
| US-9079885-B2 | Fluorescent isoindoline dyes | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-20120153266-A1 | FLUORESCENT ISOINDOLINE DYES | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2012-06-21 | — | — | US | disclosed |
| WO-1999065961-A1 | HOLE INJECTOR POLYMERS | THOMSON-CSF (FR) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | OCIAD1, OCIAD2, OXA1L | HTR2A 2131/4885TRPM4 97/4885ALDH1A1 1077/4885 |
| US-20120153266-A1 | FLUORESCENT ISOINDOLINE DYES | OCIAD1, OCIAD2, OXA1L | HTR2A 2131/4885TRPM4 97/4885ALDH1A1 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.