Sugi Predict

Sugi Predict / Compounds / SCHEMBL615452

SCHEMBL615452

SCHEMBL615452

OCc1cc2ccccc2c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPM4 Q8TD43 1/20 0.54
▸ ALDH1A1 P00352 5/20 0.48
▸ HSD17B10 Q99714 3/20 0.48
▸ HIF1A Q16665 1/20 0.48
▸ CYP1B1 Q16678 1/20 0.48
▸ HPRT1 P00492 1/20 0.46
▸ MAPT P10636 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ RAD52 P43351 1/20 0.44
▸ TAAR1 Q96RJ0 1/20 0.44
▸ CYP2A6 P11509 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ CYP1A2 P05177 3/20 0.43
▸ HTR2A P28223 1/20 0.41
▸ NQO2 P16083 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ KDM4E B2RXH2 3/20 0.41
▸ MEN1 O00255 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2311037 0.85 TRPM4 (0.48) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL10645866 0.85 HPRT1 (0.58) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL18179348 0.81 TRPM4 (0.43) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL9475347 0.80 CHEK1 (0.50) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL430273 0.79 PDE4A (0.46) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL29583446 0.79 PDE4A (0.46) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL18138405 0.79 TRPM4 (0.46) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL22824165 0.79 TRPM4 (0.46) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL598643 0.79 TRPM4 (0.46) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL8517693 0.79 HTR2A (0.56) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359656-A Copper-catalyzed stannization reaction method for carbon-oxygen bond cleavage of aryl methanol 天津师范大学 2024-07-19 — — CN disclosed
US-11220482-B2 Aminopyridinemethanol compounds and their use UNIVERSITE AMIENS PICARDIE JULES VERNE (FR) 2022-01-11 — — US disclosed
EP-3704093-A1 NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE Université Amiens Picardie Jules Verne (FR) 2020-09-09 — — EP disclosed
US-20200255379-A1 NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE UNIV AMIENS PICARDIE JULES VERNE (FR) 2020-08-13 — — US disclosed
CN-106947381-B A kind of Polyacrylate/polyurethane fluorescent paint and preparation method thereof 中国科学技术大学 2019-04-16 — — CN disclosed
CN-106700084-A Diphenolic acid-based polyphosphate ester flame retardant containing DOPO structure and preparation method of flame retardant 浙江大学宁波理工学院 2017-05-24 — — CN disclosed
US-8486959-B2 Dibenzo[f,h]isoquinoline derivatives NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2013-07-16 — — US disclosed
US-8383154-B2 Swellable dosage form comprising gellan gum EGALET A/S (DK) 2013-02-26 — — US disclosed
US-8383155-B2 Swellable dosage form comprising gellan gum EGALET A/S (DK) 2013-02-26 — — US disclosed
US-20120039969-A1 SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM EGALET A/S 2012-02-16 — — US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 — — US disclosed
CN-101402582-A Synthesis of alpha-hydroxyl-beta-aminophenol with optical activity UNIV EAST CHINA NORMAL (CN) 2009-04-08 — — CN disclosed
US-20080299199-A1 Swellable Dosage Form Comprising Gellan Gum EGALET A/S 2008-12-04 — — US disclosed
EP-1758557-A2 SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM Egalet A/S (DK) 2007-03-07 — — EP disclosed
CN-1765866-A 1,3-dichlor-6-trifluomethyl-9-phenanthrene formaldehyde preparation method ZHEJIANG NHU CO LTD (CN) 2006-05-03 — — CN disclosed
WO-2005107713-A2 SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM EGALET A/S (DK) 2005-11-17 — — WO disclosed
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 — — US disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 — — EP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 — — US disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120039969-A1 SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM PUF60, COG6, GP6 TRPM4 3621/4885ALDH1A1 3593/4885HSD17B10 3647/4885
US-11220482-B2 Aminopyridinemethanol compounds and their use QDPR, PNMT, CYP3A43 TRPM4 378/4885ALDH1A1 472/4885HSD17B10 2999/4885
US-20200255379-A1 NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE QDPR, PNMT, CYP3A43 TRPM4 241/4885ALDH1A1 736/4885HSD17B10 2837/4885
US-20080299199-A1 Swellable Dosage Form Comprising Gellan Gum GP6, PUF60, SELL TRPM4 3645/4885ALDH1A1 3639/4885HSD17B10 3834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.