Phthalic Acid

Phthalic Acid

SCHEMBL8517832

C=CC(C=O)CC.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
ALOX15 P16050 1/20 0.47
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
KMT2A Q03164 4/20 0.39
AKR1C3 P42330 2/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 2/20 0.39
RECQL P46063 1/20 0.39
MYC P01106 2/20 0.38
NR4A1 P22736 1/20 0.38
HPGD P15428 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
HMGB1 P09429 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11124201 0.80 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1
Phthalic Acid SCHEMBL368309 0.79 ALDH1A1 (0.50) ALDH1A1ALOX15POLBTDP1MAPT
Phthalic Acid SCHEMBL27350994 0.76 ALDH1A1 (0.61) ALDH1A1ALOX15TDP1MAPTHDAC8
SCHEMBL38438 0.75
Phthalic Acid SCHEMBL797300 0.75 ALDH1A1 (0.48) ALDH1A1ALOX15TDP1MAPTHDAC8
Phthalic Acid SCHEMBL6065205 0.74 ALDH1A1 (0.64) ALDH1A1ALOX15POLBTDP1MAPT
Phthalic Acid SCHEMBL28144626 0.74 ALDH1A1 (0.64) ALDH1A1ALOX15POLBTDP1MAPT
Phthalic Acid SCHEMBL2171614 0.74 ALDH1A1 (0.64) ALDH1A1ALOX15POLBTDP1MAPT
Phthalic Acid SCHEMBL9015682 0.73 ALDH1A1 (0.70) ALDH1A1ALOX15POLBMAPTHDAC8
Phthalic Acid SCHEMBL9015687 0.73 ALDH1A1 (0.70) ALDH1A1ALOX15POLBMAPTHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554006-B1 Polyunsaturated diazonium compounds AGFA GEVAERT NV (BE) 1999-04-28 EP disclosed
US-5534623-A NEGATIVE WORKING RADIATION SENSITIVE COMPOSITIONS DU PONT (UK) LIMITED (GB) 1996-07-09 US disclosed
US-5466789-A Negative-working, radiosensitivity; lithography; printing plates; photopolymerizable DU PONT (UK) LIMITED (GB) 1995-11-14 US disclosed
EP-0554006-A1 Polyunsaturated diazonium compounds Du Pont (UK) Limited (GB) 1993-08-04 EP disclosed