Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611244 | 0.76 | P2RX7 (0.61) | P2RX7GRM4ADORA3GSK3AGSK3B | |
| SCHEMBL1008439 | 0.67 | P2RX7 (0.48) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| SCHEMBL17394915 | 0.67 | P2RX7 (0.48) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| SCHEMBL1008438 | 0.67 | P2RX7 (0.48) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| SCHEMBL17394912 | 0.67 | P2RX7 (0.48) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| SCHEMBL1008440 | 0.63 | P2RX7 (0.48) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| Trifluoroacetic Acid SCHEMBL27742143 | 0.63 | P2RX7 (0.49) | P2RX7GRM4TBXA2R | |
| Trifluoroacetic Acid SCHEMBL30581171 | 0.63 | P2RX7 (0.49) | P2RX7GRM4TBXA2R | |
| SCHEMBL24579548 | 0.63 | P2RX7 (0.52) | P2RX7GRM4HSP90AA1HKDC1TBXA2R | |
| SCHEMBL8022617 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432780-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010134478-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | WO | disclosed |