Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312709 | 1.00 | LMNA (0.36) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL9312712 | 1.00 | LMNA (0.36) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL8517879 | 1.00 | LMNA (0.36) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL8517258 | 0.88 | LMNA (0.35) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL8517254 | 0.88 | LMNA (0.35) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL9311921 | 0.88 | LMNA (0.35) | LMNAPOLBSMN1; SMN2CNR1MAOB | |
| SCHEMBL9312335 | 0.87 | PDGFRB (0.32) | CNR1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL9312309 | 0.87 | PDGFRB (0.32) | CNR1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL9312319 | 0.87 | PDGFRB (0.32) | CNR1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL9312325 | 0.87 | PDGFRB (0.32) | CNR1NPC1RAB9APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |