Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349346 | 0.97 | TSHR (0.68) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL4310722 | 0.85 | TSHR (0.84) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL7218802 | 0.82 | HPGD (0.73) | TSHRHPGDAKR1C1NPC1LMNA | |
| Ethylene SCHEMBL8381547 | 0.81 | HPGD (0.54) | HPGDLMNAALDH1A1HTTALOX15 | |
| SCHEMBL29941490 | 0.81 | HPGD (0.71) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL10197843 | 0.81 | HPGD (0.71) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL1588162 | 0.80 | TSHR (0.69) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL31428791 | 0.78 | TSHR (0.68) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL1375290 | 0.78 | TSHR (0.68) | TSHRHPGDAKR1C1NPC1LMNA | |
| SCHEMBL4548025 | 0.78 | TSHR (1.00) | TSHRHPGDAKR1C1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |