Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 12/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8547928 | 0.99 | PLG (0.44) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8546417 | 0.88 | MEN1 (0.36) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8548363 | 0.88 | PLAU (0.39) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8374823 | 0.83 | PLAU (0.47) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8549377 | 0.83 | PLG (0.55) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8548609 | 0.82 | PLAU (0.44) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8547382 | 0.82 | PLAU (0.46) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8518061 | 0.82 | PLAU (0.42) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8546931 | 0.81 | PLAU (0.41) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8551931 | 0.81 | PLG (0.53) | PLGKMT2AMEN1ALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950418-A2 | Composition for preventing or treating ischemic disease | Takeda Chemical Industries, Ltd. (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |