Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8550948 | 0.98 | PLG (0.51) | PLGKMT2AALDH1A1MEN1RAD52 | |
| SCHEMBL8547926 | 0.87 | ALDH1A1 (0.51) | PLGKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8547084 | 0.84 | PLAU (0.51) | PLGKMT2AALDH1A1MEN1RAD52 | |
| Hydrochloric Acid SCHEMBL8549050 | 0.82 | MEN1 (0.50) | PLGKMT2AALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL8549377 | 0.81 | PLG (0.55) | PLGKMT2AALDH1A1MEN1RAD52 | |
| SCHEMBL8374823 | 0.81 | PLAU (0.47) | PLGKMT2AALDH1A1MEN1RAD52 | |
| SCHEMBL8518199 | 0.81 | PLG (0.45) | PLGKMT2AALDH1A1MEN1RAD52 | |
| Hydrochloric Acid SCHEMBL8547382 | 0.79 | PLAU (0.46) | PLGKMT2AALDH1A1MEN1RAD52 | |
| Hydrochloric Acid SCHEMBL8548609 | 0.79 | PLAU (0.44) | PLGKMT2AALDH1A1MEN1RAD52 | |
| Hydrochloric Acid SCHEMBL8547928 | 0.79 | PLG (0.44) | PLGKMT2AALDH1A1MEN1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |