Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311825 | 1.00 | AURKA (0.41) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL8518231 | 1.00 | AURKA (0.41) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL8518233 | 1.00 | AURKA (0.41) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL8518128 | 0.89 | AURKA (0.40) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL9313421 | 0.89 | AURKA (0.40) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL8518126 | 0.89 | AURKA (0.40) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL8517788 | 0.88 | RAB9A (0.37) | KCNH2RAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL8517790 | 0.88 | RAB9A (0.37) | KCNH2RAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL8517786 | 0.88 | RAB9A (0.37) | KCNH2RAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL8517924 | 0.88 | SMN1; SMN2 (0.45) | METCYP11B1CYP11B2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |