Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | USP1 | O94782 | 1/20 | 0.48 |
| ▸ | USP8 | P40818 | 1/20 | 0.48 |
| ▸ | OTUB1 | Q96FW1 | 1/20 | 0.48 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116254 | 0.90 | CYP19A1 (0.45) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL14736710 | 0.85 | USP2 (0.48) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL14736234 | 0.85 | USP2 (0.48) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL14736291 | 0.82 | USP2 (0.46) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL14736207 | 0.81 | USP2 (0.48) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL13633903 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KMT2AMEN1F2 | |
| Hydrochloric Acid SCHEMBL2819349 | 0.80 | CYP2A6 (0.55) | ALDH1A1HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14736549 | 0.79 | IKBKB (0.50) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL14764298 | 0.75 | USP2 (0.48) | USP2USP1USP8OTUB1USP36 | |
| SCHEMBL266619 | 0.74 | KDM4E (0.66) | KMT2AMEN1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945539-A | ENZYME INHIBITOR | JAPAN TOBACCO, INC. (JP) | 1999-08-31 | — | — | US | disclosed |