Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835168 | 0.75 | PDE10A (0.43) | PDE10A | |
| SCHEMBL10144470 | 0.75 | PDE10A (0.43) | PDE10A | |
| SCHEMBL20144422 | 0.74 | — | — | |
| SCHEMBL29496406 | 0.73 | MAPK1 (0.32) | PDE10A | |
| SCHEMBL3457245 | 0.73 | MAPK1 (0.32) | PDE10A | |
| SCHEMBL582880 | 0.71 | ERBB2 (0.31) | PDE10A | |
| SCHEMBL26492489 | 0.71 | KDM4E (0.32) | PDE10A | |
| SCHEMBL28208820 | 0.71 | PDE10A (0.30) | PDE10A | |
| SCHEMBL8521432 | 0.71 | PDE10A (0.30) | PDE10A | |
| SCHEMBL29792794 | 0.71 | KDM4E (0.39) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321259-B1 | NEW PYRAZINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF | GUANGZHOU MAGPIE PHARMACEUTICAL CO LTD (CN) | 2023-10-04 | — | — | EP | disclosed |
| EP-3321259-A1 | NEW PYRAZINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF | Guangzhou Magpie Pharmaceutical Co., Ltd. (CN) | 2018-05-16 | — | — | EP | disclosed |
| WO-2012065527-A1 | COMPOUDS AND USES AS L-TYPE CALCIUM CHANNEL BLOCKER AND/OR ACETYLCHOLINESTERASE INHIBITOR THEREOF | 江苏先声药物研究有限公司 (CN) | 2012-05-24 | — | — | WO | disclosed |
| EP-2213666-B1 | LIGUSTRAZINE AROMATIC ACID ETHER DERIVATIVE, ITS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION | LI JIAMING (CN) | 2012-02-15 | — | — | EP | disclosed |