SCHEMBL8518658

SCHEMBL8518658

CC(C)OC(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10915201 0.80
SCHEMBL22395481 0.79
SCHEMBL12770552 0.78
SCHEMBL14612082 0.78
SCHEMBL10915072 0.78
SCHEMBL5870578 0.78
SCHEMBL9587626 0.77 LMNA (0.33)
SCHEMBL15486360 0.77 LMNA (0.33)
SCHEMBL1149041 0.75
SCHEMBL1149021 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787800-B2 BRD9 degraders and uses thereof FOGHORN THERAPEUTICS INC. (US) 2023-10-17 US disclosed
US-11773085-B2 Methods and compounds for treating disorders FOGHORN THERAPEUTICS INC. (US) 2023-10-03 US disclosed
US-20230276701-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE OSAKA UNIVERSITY (JP) 2023-08-31 US disclosed
US-20230276701-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE OSAKA UNIVERSITY (JP) 2023-08-31 US disclosed
CN-115746193-B Low-surface-energy fluorocarbon polymer for fire protection of transformer substation and preparation method thereof 国网安徽省电力有限公司电力科学研究院 2023-08-01 CN disclosed
CN-115746193-A Low-surface-energy fluorocarbon polymer for transformer substation fire protection and preparation method thereof 国网安徽省电力有限公司电力科学研究院 2023-03-07 CN disclosed
US-20230065463-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-03-02 US disclosed
US-20220048906-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2022-02-17 US disclosed
WO-2022025880-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2022-02-03 WO disclosed
WO-2021022163-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-02-04 WO disclosed
US-20210009568-A1 METHODS AND COMPOUNDS FOR TREATING DISORDERS FOGHORN THERAPEUTICS INC. 2021-01-14 US disclosed
WO-2020160196-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2020-08-06 WO disclosed
WO-2020160193-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2020-08-06 WO disclosed
US-5864968-A Shoe with perfluoropolyether insole MANN MORRIS A (US) 1999-02-02 US disclosed