Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305358 | 0.98 | GAA (0.38) | GAATSHRTHRB | |
| SCHEMBL1140660 | 0.90 | GAA (0.37) | GAATSHRTHRB | |
| SCHEMBL10877043 | 0.88 | GAA (0.32) | GAA | |
| SCHEMBL22562148 | 0.76 | GNAI3 (0.36) | TSHR | |
| SCHEMBL10643924 | 0.73 | GAA (0.33) | GAA | |
| SCHEMBL27695743 | 0.71 | GAA (0.36) | GAATSHRTHRB | |
| SCHEMBL27695750 | 0.71 | GAA (0.36) | GAATSHRTHRB | |
| SCHEMBL28767398 | 0.71 | GAA (0.36) | GAATSHRTHRB | |
| SCHEMBL27695900 | 0.71 | GAA (0.36) | GAATSHRTHRB | |
| SCHEMBL27715715 | 0.71 | GAA (0.36) | GAATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874627-A | Process for preparing polyamine derivatives and intermediates thereof | MERRELL PHARMACEUTICALS INC. (US) | 1999-02-23 | — | — | US | claimed |
| WO-1995009832-A1 | NOVEL PROCESS FOR PREPARING POLYAMINE DERIVATIVES AND INTERMEDIATES THEREOF | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5874627-A | Process for preparing polyamine derivatives and intermediates thereof | MERRELL PHARMACEUTICALS INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5756739-A | Process for preparing polyamine derivative and intermediates thereof | MERRELL PHARMACEUTICALS INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1995009832-A1 | NOVEL PROCESS FOR PREPARING POLYAMINE DERIVATIVES AND INTERMEDIATES THEREOF | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-13 | — | — | WO | disclosed |