Ethyl Oleate — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Ethyl Oleate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CHRM1 known ✓	P11229	1/20	0.54

▸	SLC6A2 known ✓	P23975	1/20	0.54

▸	HSD17B10	Q99714	3/20	0.65

▸	CYP3A4	P08684	2/20	0.65

▸	ALOX15	P16050	2/20	0.65

▸	ALDH1A1	P00352	1/20	0.65

▸	TSHR	P16473	1/20	0.65

▸	TDP1	Q9NUW8	1/20	0.65

▸	FAAH	O00519	4/20	0.62

▸	DGKA	P23743	1/20	0.58

▸	PRKCE	Q02156	1/20	0.56

▸	PRKCQ	Q04759	1/20	0.56

▸	PRKCD	Q05655	1/20	0.56

▸	PRKCA	P17252	1/20	0.56

▸	PGR	P06401	2/20	0.55

▸	ADORA3	P0DMS8	2/20	0.55

▸	NR1I2	O75469	1/20	0.55

▸	PTGS2	P35354	1/20	0.55

▸	PDE4D	Q08499	1/20	0.55

▸	TERT	O14746	3/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Ethyl Oleate SCHEMBL8518938	1.00	HSD17B10 (0.65)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
Ethyl Oleate SCHEMBL14763720	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL8982640	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL10481167	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL358161	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL25490302	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL8982772	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
Ethyl Oleate SCHEMBL16163583	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL7557821	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL8982687	0.93	HSD17B10 (0.73)	HSD17B10CYP3A4ALOX15ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5049192-A	Fatty ester, neutralized sulfonated fatty acid or ester	VICTORIAN CHEMICAL CO. PTY. LTD. (AU)	1991-09-17	—	—	US	claimed
US-6008157-A	WITH HEAT RESISTANT SLIP LAYER CONTAINING INORGANIC FILLER	DAI NIPPON PRINTING CO., LTD. (JP)	1999-12-28	—	—	US	disclosed
EP-0704319-B1	Thermal transfer sheet	DAINIPPON PRINTING CO LTD (JP)	1998-06-10	—	—	EP	disclosed
US-5714434-A	INCLUDING HEAT RESISTANT SLIP LAYER CONTAINING PARTICLES HAVING SPECIFIED SHOT-TYPE ABRASION LOSS	DAI NIPPON PRINTING CO., LTD. (JP)	1998-02-03	—	—	US	disclosed
EP-0704319-A1	Thermal transfer sheet	DAI NIPPON PRINTING CO., LTD. (JP)	1996-04-03	—	—	EP	disclosed
US-5049192-A	Fatty ester, neutralized sulfonated fatty acid or ester	VICTORIAN CHEMICAL CO. PTY. LTD. (AU)	1991-09-17	—	—	US	disclosed