SCHEMBL8519213

SCHEMBL8519213

O=C(OF)C(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8728222 0.78
SCHEMBL150679 0.72 ALDH1A1 (0.44)
SCHEMBL672469 0.72 ALDH1A1 (0.44)
SCHEMBL28207405 0.71
SCHEMBL28821507 0.69 ALDH1A1 (0.41)
SCHEMBL152334 0.69
SCHEMBL114625 0.69
SCHEMBL28329124 0.69 ALDH1A1 (0.41)
SCHEMBL322207 0.69
SCHEMBL28254434 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008306-A COMPOSITION OF STRAINED CYCLOOLEFIN AND A DIVALENT CATIONIC RUTHENIUM OR OSMIUM BOUND TO 1-3 TERTIARY PHOSPHINE LIGANDS, THE PHOSPHINE GROUPS CONTAIN PHENYL SUBSTITUTED BY ALKYL, ALKOXY OR HALOALKYL GROUPS; IMPROVED CATALYTIC ACTIVITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-12-28 US disclosed
US-4548976-A Bis-(norbornyl or substituted norbornyl) derivatives of a phenol or a phenylamine, process for their preparation and compositions containing same THE DOW CHEMICAL COMPANY (US) 1985-10-22 US disclosed
EP-0126193-A1 Bis-(norbornyl or substituted norbornyl) derivatives of a phenol or a phenylamine, process for their preparation and compositions containing same THE DOW CHEMICAL COMPANY (US) 1984-11-28 EP disclosed