SCHEMBL8519612

SCHEMBL8519612

Cc1ccc(C)c2c1OBO2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15845261 0.69
SCHEMBL15746268 0.67 TSHR (0.41) CYP1A2TSHR
SCHEMBL6127936 0.65 ADORA2A (0.31)
SCHEMBL6127806 0.62 NQO2 (0.37) CYP1A2TSHRACHE
SCHEMBL8519614 0.62 CYP1A2 (0.32) CYP1A2TSHRACHE
SCHEMBL8405560 0.62 ITGB2 (0.36) CYP1A2TSHRACHE
SCHEMBL12422694 0.61 BRD4 (0.32) CYP1A2
SCHEMBL15747133 0.60 ALDH1A1 (0.38)
SCHEMBL10784626 0.59
SCHEMBL3424471 0.59 AHR (0.50) CYP1A2TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed