Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 1.00 |
| ▸ | CA2 | P00918 | 16/20 | 1.00 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439925 | 0.80 | CA2 (0.68) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL5684413 | 0.78 | CA1 (0.64) | CA1CA2CA12CA9KIF11 | |
| SCHEMBL6352180 | 0.78 | CA1 (0.64) | CA1CA2CA12CA9KIF11 | |
| SCHEMBL4591628 | 0.78 | CA1 (0.64) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL1122831 | 0.76 | CA1 (0.61) | CA1CA2CA12CA9KIF11 | |
| SCHEMBL1645913 | 0.76 | CA1 (1.00) | CA1CA2CA12CA9KIF11 | |
| SCHEMBL28472964 | 0.76 | CA2 (1.00) | CA1CA2CA12CA9 | |
| SCHEMBL21033856 | 0.76 | CA1 (0.61) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL518114 | 0.76 | CA1 (0.61) | CA1CA2CA12CA9KIF11 | |
| SCHEMBL28750070 | 0.76 | CA1 (1.00) | CA1CA2CA12CA9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785018-A | Preparation method of febuxostat decarboxylated impurities | 湖北广济药业股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-112961118-A | Synthesis method of febuxostat decarboxylation impurities | 廊坊师范学院 | 2021-06-15 | — | — | CN | disclosed |
| US-5932407-A | COLOR PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| US-4525451-A | COLOR STAIN INHIBITORS IN SILVER HALIDES | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |