Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423120 | 0.88 | USP2 (0.46) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL8422870 | 0.85 | USP2 (0.44) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL8425981 | 0.83 | USP2 (0.42) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL21925 | 0.79 | USP2 (0.47) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL7643515 | 0.79 | USP2 (0.47) | USP2MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL192788 | 0.79 | TP53 (0.51) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL8426424 | 0.79 | TDP1 (0.43) | USP2ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL8406727 | 0.78 | USP2 (0.46) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL8406726 | 0.77 | USP2 (0.45) | USP2MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL5712364 | 0.76 | ALDH1A1 (0.59) | USP2MAPK1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946095-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026664-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |