Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391065 | 0.76 | GABRA1 (0.61) | PGRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL3259073 | 0.76 | GABRA1 (0.61) | PGRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30865023 | 0.75 | GABRA1 (0.46) | DAOGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28124567 | 0.75 | GABRA1 (0.46) | DAOGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10027162 | 0.74 | PARP1 (0.41) | PGRALDH1A1MAPTPARP1HPGD | |
| SCHEMBL10822678 | 0.69 | HDAC8 (0.50) | DAOHTR5ACA1CA2CA7 | |
| SCHEMBL10629910 | 0.69 | DAO (0.49) | DAOPOLBCREBBPAGTR1ALDH1A1 | |
| SCHEMBL3088689 | 0.67 | DAO (1.00) | DAOPOLBAGTR1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL11430657 | 0.66 | DAO (0.96) | DAOPOLBAGTR1ALDH1A1GAA | |
| SCHEMBL8561720 | 0.66 | MEN1 (0.51) | POLBGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |