Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737649 | 0.91 | KDM4E (0.44) | POLBHTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL64071 | 0.84 | NOTUM (0.43) | POLBNOTUMCYP2C9HSD17B3 | |
| SCHEMBL15782147 | 0.75 | KDM4E (0.40) | POLBHTTKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL8534601 | 0.75 | POLB (0.41) | POLBHTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11174570 | 0.74 | NOTUM (0.37) | POLBNOTUMCYP2C9HSD17B3 | |
| SCHEMBL14752964 | 0.72 | CHRNB2 (0.40) | POLBHTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7953388 | 0.72 | KDM4E (0.45) | POLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27313269 | 0.71 | KDM4E (0.37) | POLBHTTKDM4ESMN1; SMN2TSHR | |
| SCHEMBL6959243 | 0.70 | — | — | |
| SCHEMBL11591344 | 0.68 | POLB (0.66) | POLBHTTNOTUMMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729504-B1 | BLEACH ACTIVATOR COMPOSITIONS | WARWICK INT GROUP (GB) | 1999-07-28 | — | — | EP | disclosed |
| EP-0682695-B1 | OXIDISING AGENTS | WARWICK INT GROUP (GB) | 1997-10-29 | — | — | EP | disclosed |