SCHEMBL8520109

SCHEMBL8520109

C=CCOC(=O)C(=CC(=O)O)C(CC)S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL850325 0.99 TSHR (0.32) TSHRTDP1
SCHEMBL1414789 0.86 TSHR (0.31) TSHR
SCHEMBL3176004 0.76 RECQL (0.30) RECQL
SCHEMBL7218817 0.75
SCHEMBL9706918 0.71 MAPT (0.33) TSHRTDP1
SCHEMBL16416754 0.70 CYP3A4 (0.33) TSHR
SCHEMBL27766572 0.68 CASP1 (0.36) TSHRTDP1RECQL
SCHEMBL87407 0.68 CASP1 (0.36) TSHRTDP1RECQL
SCHEMBL1077784 0.68 CASP1 (0.36) TSHRTDP1RECQL
SCHEMBL1075821 0.68 TSHR (0.38) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5898043-A CONSISTS OF A FILM FORMING RESIN AND A CROSSLINKING AGENT CAPABLE OF FORMING CROSSLINKED RESIN POWDER HAS A SPECIFIC VOLUME-AVERAGE PARTICLE DIAMETER AND SHAPE FACTOR 100.5 TO 160 NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1999-04-27 US disclosed
EP-0751192-A1 POWDER PAINT, METHOD OF MANUFACTURING THE SAME, AND METHOD OF PAINTING USING THE PAINT NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1997-01-02 EP disclosed