Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benz(B)Anthracene SCHEMBL9710284 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1SLC15A1 | |
| SCHEMBL31572200 | 0.76 | GRIN2D (0.52) | POLBDAOKDM4ENPC1USP2 | |
| SCHEMBL11200843 | 0.76 | GRIN2D (0.52) | POLBDAOKDM4ENPC1USP2 | |
| Valine SCHEMBL8606825 | 0.75 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1SLC15A1 | |
| Anthraquinone SCHEMBL3654040 | 0.73 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2SLC1A1ELANE | |
| Anthraquinone SCHEMBL27983859 | 0.73 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2SLC1A1ELANE | |
| Biphenyl SCHEMBL27824248 | 0.73 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1GAA | |
| Biphenyl SCHEMBL2494151 | 0.73 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1GAA | |
| Valine SCHEMBL28726 | 0.72 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1AKR1B1 | |
| Valine SCHEMBL11319001 | 0.72 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440787-B1 | COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR INVESTIGACION (ES) | 1999-10-13 | — | — | EP | disclosed |
| EP-0440787-A1 | NEW COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1991-08-14 | — | — | EP | disclosed |