Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622272 | 0.96 | — | — | |
| SCHEMBL7535064 | 0.85 | SMN1; SMN2 (0.39) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7536167 | 0.81 | LMNA (0.42) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7108652 | 0.81 | LMNA (0.42) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7532323 | 0.81 | LMNA (0.42) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL1493706 | 0.81 | LMNA (0.42) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Bromide SCHEMBL21591030 | 0.72 | — | — | |
| SCHEMBL14902866 | 0.70 | — | — | |
| SCHEMBL20534764 | 0.67 | — | — | |
| SCHEMBL7584514 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958906-A | Phospholipid derivatives containing higher elements of the fifth main group | ASTA-MEDICA AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |