SCHEMBL852028

SCHEMBL852028

O=C(O)c1ccsc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27487459 0.96 TSHR (0.47)
Pyridine SCHEMBL28497450 0.87 TSHR (0.40)
SCHEMBL1791803 0.79
SCHEMBL2179880 0.79
SCHEMBL15263400 0.79
SCHEMBL18719423 0.77 POLB (0.41)
SCHEMBL15276735 0.75 MEN1 (0.50)
SCHEMBL1450859 0.74 KMT2A (0.51)
SCHEMBL1347070 0.74 ALDH1A1 (0.44)
SCHEMBL27659893 0.74 HSP90AB1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638961-A Six-epoxy-group penta dithiophene derivative sulfur coordination metal copolymer complex and preparation method and application thereof 湘潭大学 2025-03-18 CN claimed
CN-119591843-A Six cyanoacrylate-based glutaryl dithiophene copolymerized sulfur coordination metal complex and preparation method and application thereof 湘潭大学 2025-03-11 CN claimed
CN-119562746-A Perovskite thin film, perovskite solar cell, preparation method and application 天合光能股份有限公司 2025-03-04 CN claimed
CN-113429381-B Bithiophene rotor derivative 3 '-acetyl- [2,2' -bithiophene ] -3-formaldehyde and preparation method and application thereof 山西大同大学 2023-03-21 CN claimed
CN-115745805-A Synthetic method of phenanthrene and naphthocycloheptene compounds 南通大学 2023-03-07 CN claimed
CN-113429381-A Bithiophene rotor derivative 3 '-acetyl- [2,2' -bithiophene ] -3-formaldehyde, preparation method and application 山西大同大学 2021-09-24 CN claimed
CN-110128633-B Preparation method and application of low-HOMO energy level polymer donor material 南昌大学 2021-01-29 CN claimed
CN-110128633-A A kind of preparation method and application of low HOMO energy level polymer donor material 南昌大学 2019-08-16 CN claimed
CN-101279974-A Pyrazolopyrimidinone derivatives, preparation and application thereof UNIV ZHONGSHAN (CN) 2008-10-08 CN claimed
US-12552757-B2 NRF2-activating compound SENJU PHARMACEUTICAL CO., LTD. (JP) 2026-02-17 US disclosed
CN-119371416-B Synthesis method for constructing 4-substituted isocoumarin and analogues thereof through oxetane ring opening 上海达歌生物医药科技有限公司 2025-05-30 CN disclosed
US-20250144094-A1 THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF ERASCA, INC. 2025-05-08 US disclosed
CN-119638961-A Six-epoxy-group penta dithiophene derivative sulfur coordination metal copolymer complex and preparation method and application thereof 湘潭大学 2025-03-18 CN disclosed
CN-119591843-A Six cyanoacrylate-based glutaryl dithiophene copolymerized sulfur coordination metal complex and preparation method and application thereof 湘潭大学 2025-03-11 CN disclosed
EP-1016664-A1 FUSED THIOPHENE COMPOUNDS AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-07-05 EP disclosed
US-5840917-A ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 US disclosed
WO-1998042347-A1 PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-01 WO disclosed
EP-0852498-A1 PHOSPHORYLAMIDES, THEIR PREPARATION AND USE Takeda Chemical Industries, Ltd. (JP) 1998-07-15 EP disclosed
WO-1997011705-A1 PHOSPHORYLAMIDES, THEIR PREPARATION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-04-03 WO disclosed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 US disclosed