Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921870 | 0.84 | SLC22A6 (0.45) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL23002878 | 0.81 | GRIK1 (0.40) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL4161257 | 0.79 | SLC22A6 (0.41) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL12056166 | 0.79 | — | — | |
| SCHEMBL1245907 | 0.79 | SLC22A6 (0.41) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL28443283 | 0.79 | SLC22A6 (0.41) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL16488286 | 0.77 | — | — | |
| SCHEMBL7407058 | 0.75 | GRIK1 (0.40) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL3183276 | 0.75 | GRIK1 (0.45) | GRIK1GRIK2GRM1GRM2SLC22A6 | |
| SCHEMBL17636172 | 0.75 | GABRR1 (0.42) | GRIK1GRIK2GRM1GRM2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455457-A2 | Covalent tethering of functional groups to proteins | PROMEGA CORPORATION (US) | 2012-05-23 | — | — | EP | disclosed |