Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245907 | 1.00 | SLC22A6 (0.41) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL17921870 | 0.88 | SLC22A6 (0.45) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL4161257 | 0.83 | SLC22A6 (0.41) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL16138447 | 0.79 | ALOX15 (0.39) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL3183276 | 0.79 | GRIK1 (0.45) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL8520307 | 0.79 | GRIK1 (0.43) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL7407055 | 0.79 | GRIK1 (0.40) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL17636172 | 0.79 | GABRR1 (0.42) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL7407058 | 0.79 | GRIK1 (0.40) | SLC22A6GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL7733980 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120449-A | Combination therapy for cancer treatment | 医睿世康药业研发公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117098537-A | Combination therapy for cancer treatment | 医睿世康药业研发公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117083283-A | Combination therapy for cancer treatment | 医睿世康药业研发公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114373510-A | Metabolic marker for lung cancer diagnosis or monitoring and screening method and application thereof | 武汉迈特维尔生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-111505189-A | Method for establishing influence of amoxicillin concentration on lactobacillus acidophilus based on metabonomics | 广西医科大学 | 2020-08-07 | — | — | CN | disclosed |