SCHEMBL8520432

SCHEMBL8520432

OCC1(c2ccccc2)CCN1c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.37
POLB P06746 1/20 0.36
CFB P00751 1/20 0.35
HSD11B1 P28845 3/20 0.34
OPRM1 P35372 3/20 0.34
SLC6A9 P48067 1/20 0.34
GAA P10253 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
PNMT P11086 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BDKRB2 P30411 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
CYP2B6 P20813 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606912 0.90 CFB (0.39) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL246216 0.90 CFB (0.39) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL606913 0.90 CFB (0.39) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL29908655 0.90 CFB (0.39) OPRL1POLBCFBHSD11B1OPRM1
Hydrochloric Acid SCHEMBL9257449 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL28282470 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL9561702 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1
Hydrochloric Acid SCHEMBL28274724 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1
Hydrochloric Acid SCHEMBL8207460 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1
SCHEMBL27866641 0.88 CFB (0.38) OPRL1POLBCFBHSD11B1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713848-B1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY (JP) 1999-09-08 EP disclosed
EP-0713848-A1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS Company, Limited (JP) 1996-05-29 EP disclosed