Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282470 | 1.00 | CFB (0.38) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL606913 | 0.98 | CFB (0.39) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL606912 | 0.98 | CFB (0.39) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL246216 | 0.98 | CFB (0.39) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL29908655 | 0.98 | CFB (0.39) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| Hydrochloric Acid SCHEMBL28274724 | 0.97 | CFB (0.38) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL27866641 | 0.97 | CFB (0.38) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| Hydrochloric Acid SCHEMBL9257449 | 0.97 | CFB (0.38) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| Hydrochloric Acid SCHEMBL8207460 | 0.97 | CFB (0.38) | CFBOPRL1OPRM1SLC6A9NR1H2 | |
| SCHEMBL2190183 | 0.92 | CFB (0.36) | CFBOPRL1OPRM1SLC6A9NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264585-A | Reaction of diarylmethanol with boroxanine | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-5189177-A | Chiral boron catalysts for reduction of ketones and process for their preparation | MERCK & CO., INC. (US) | 1993-02-23 | — | — | US | disclosed |