SCHEMBL8520502

SCHEMBL8520502

COc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.57
ALDH1A1 P00352 1/20 0.52
GDA Q9Y2T3 1/20 0.51
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
GRIA4 P48058 1/20 0.49
XDH P47989 6/20 0.48
PDE5A O76074 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682654 0.98 PNP (0.56) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL1898182 0.77 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL27496341 0.76 GDA (0.62) PNPGDAXDH
SCHEMBL29793761 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL8230113 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
Xanthine SCHEMBL29180270 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL94917 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL612168 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL612210 0.73 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
Guanine SCHEMBL1264884 0.73 PNP (1.00) PNPALDH1A1GDAGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938587-A1 PORTABLE APPARATUS AND METHOD FOR DETECTION OF METHYLXANTHINE CHEMICAL SPECIES Coffee Chek, Inc. (US) 1999-09-01 EP disclosed
WO-1996040984-A1 PORTABLE APPARATUS AND METHOD FOR DETECTION OF METHYLXANTHINE CHEMICAL SPECIES COFFEE CHEK, INC. (US) 1996-12-19 WO disclosed