Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520502 | 0.98 | PNP (0.57) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1898182 | 0.75 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27496341 | 0.74 | GDA (0.62) | PNPGDAXDH | |
| Guanine SCHEMBL27400537 | 0.74 | PNP (0.96) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Water SCHEMBL9461622 | 0.72 | PNP (0.59) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8230113 | 0.72 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Xanthine SCHEMBL29180270 | 0.72 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL612168 | 0.72 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL1264884 | 0.72 | PNP (1.00) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL94917 | 0.72 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488079-A1 | Oxadiazolylmethylpurines, their preparation, and their pharmaceutical use | CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-06-03 | — | — | EP | disclosed |