Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MANBA | O00462 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18930219 | 1.00 | LMNA (0.35) | LMNACYP1A2THPOPDE4DMANBA | |
| SCHEMBL23344024 | 0.85 | LMNA (0.37) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL7529733 | 0.85 | LMNA (0.37) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL2757776 | 0.85 | LMNA (0.37) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL15381137 | 0.83 | SPHK1 (0.39) | LMNACYP1A2THPO | |
| SCHEMBL2756249 | 0.82 | LMNA (0.41) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL2367932 | 0.82 | LMNA (0.41) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL6676888 | 0.82 | LMNA (0.41) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL1984099 | 0.82 | LMNA (0.41) | LMNACYP1A2THPOMANBATHRB | |
| SCHEMBL18596140 | 0.82 | LMNA (0.41) | LMNACYP1A2THPOMANBATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455376-A1 | Heterocyclic compounds as inhibitors of hepatitis C virus (HCV) | Abbott Laboratories (US) | 2012-05-23 | — | — | EP | disclosed |