SCHEMBL8520680

SCHEMBL8520680

C=CCS(=O)(=O)c1cccc(C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
F2 P00734 3/20 0.49
PRSS1 P07477 3/20 0.49
PRSS2 P07478 3/20 0.49
PRSS3 P35030 3/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MEP1B Q16820 2/20 0.48
MAPT P10636 1/20 0.48
IL1RN P18510 1/20 0.48
AKR1C3 P42330 3/20 0.47
AKR1C1 Q04828 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
APEX1 P27695 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43
PTK2B Q14289 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3188896 0.84 CYP2C19 (0.48) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL27547596 0.83 LCK (0.52) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL5185538 0.80 F2 (0.43) F2PRSS1PRSS2PRSS3
SCHEMBL31401470 0.80 F2 (0.54) CYP2C19ALDH1A1F2PRSS1PRSS2
SCHEMBL35184 0.80 CYP2C19 (0.55) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL29453097 0.80 CYP2C19 (0.55) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL1018533 0.80 TSHR (0.54) CYP2C19ALDH1A1F2PRSS1PRSS2
SCHEMBL29245371 0.78 F2 (0.57) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL4416606 0.78 ALDH1A1 (0.56) CYP2C19ALDH1A1LMNAF2PRSS1
SCHEMBL19071740 0.78 CYP2C19 (0.54) CYP2C19ALDH1A1LMNAF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8053409-A None JP disclosed
JP-11302249-A None JP disclosed
JP-H11302249-A PRODUCTION OF 3-ALKYLSULFONYL-4-ALKYLBENZOIC ACID ESTER TAOKA CHEM CO LTD 1999-11-02 JP disclosed
JP-H0853409-A PRODUCTION OF 5-ALKYLSULFONYLBENZOIC ACID DERIVATIVE TAOKA CHEM CO LTD 1996-02-27 JP disclosed