Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048486 | 0.93 | ACP3 (0.49) | ACP3TDP1SRCMTNR1AAKR1B1 | |
| SCHEMBL7639813 | 0.92 | ACP3 (0.48) | ACP3TDP1SRCMTNR1AAKR1B1 | |
| SCHEMBL7605396 | 0.86 | ACP3 (0.63) | ACP3TDP1SRCAKR1B1FFAR1 | |
| SCHEMBL27811913 | 0.80 | ACP3 (0.68) | ACP3TDP1MTNR1ACYP1A2MCL1 | |
| SCHEMBL8520179 | 0.79 | SRC (0.39) | SRCCYP1A2MCL1MAPTNPC1 | |
| SCHEMBL28278348 | 0.78 | ACP3 (0.44) | ACP3TDP1MTNR1AAKR1B1FFAR1 | |
| SCHEMBL5059954 | 0.77 | ACP3 (0.44) | ACP3TDP1MTNR1AAKR1B1FFAR1 | |
| SCHEMBL11772534 | 0.77 | SRC (0.57) | TDP1SRCCETPL3MBTL1 | |
| SCHEMBL3245338 | 0.76 | SRC (0.61) | TDP1SRCCETPL3MBTL1 | |
| SCHEMBL7634441 | 0.75 | FAAH (0.54) | CYP1A2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949922-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998013044-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | disclosed |