Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL8436468 | 0.81 | CYP1A2 (0.52) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| Formic Acid SCHEMBL5378796 | 0.79 | CYP1A2 (0.50) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| SCHEMBL1525601 | 0.74 | — | — | |
| SCHEMBL29881712 | 0.74 | — | — | |
| SCHEMBL109650 | 0.74 | CYP1A2 (0.62) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| SCHEMBL22081972 | 0.74 | CYP1A2 (0.62) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| SCHEMBL8380054 | 0.73 | CYP1A2 (0.44) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| Fluorene SCHEMBL27417358 | 0.73 | MAOA (0.56) | CYP1A2MAOAMAOBMAPTMEN1 | |
| Bicarbonate SCHEMBL8601125 | 0.73 | CYP1A2 (0.55) | CYP1A2MAOACYP2A6DRD2DRD1 | |
| Hydroxyamine SCHEMBL344671 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962660-A | COMPOUND WHICH SUPPRESSES SELECTIN-MEDIATED CELLULAR ADHESION; FOR STABLE ANTIINFLAMMATORY AGENTS WITH BETTER BIOAVAILABILITY AND GREATER ACTIVITY WHICH ARE EASIER TO SYNTHESIZE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0815127-A1 | FUCOPEPTIDES | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-5614615-A | Sialyl Lewis X mimetics incorporating fucopeptides | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-03-25 | — | — | US | disclosed |
| US-5599915-A | INHIBIT SELECTIN-MEDIATED CELLULAR ADHESION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996029339-A1 | FUCOPEPTIDES | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |