Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521204 | 0.96 | SLC6A2 (0.56) | CALCRLSLC6A2RENNMUR2NTSR2 | |
| SCHEMBL30585292 | 0.91 | SLC6A2 (0.60) | SLC6A2NTSR2NTSR1SORT1 | |
| SCHEMBL30512639 | 0.86 | CALCRL (0.59) | CALCRLSLC6A2RENAGTR1AGTR2 | |
| SCHEMBL8441486 | 0.85 | KDM1A (0.54) | NMUR2NTSR2NTSR1NMUR1NPY1R | |
| SCHEMBL30810418 | 0.85 | SLC6A2 (0.63) | CALCRLSLC6A2RENNMUR2AGTR1 | |
| SCHEMBL30540721 | 0.85 | NTSR1 (0.57) | SLC6A2NTSR2NTSR1SORT1NPY1R | |
| SCHEMBL29836567 | 0.84 | SLC6A2 (0.60) | CALCRLSLC6A2NMUR2AGTR1AGTR2 | |
| SCHEMBL29796577 | 0.84 | SLC6A2 (0.60) | CALCRLSLC6A2NMUR2AGTR1AGTR2 | |
| SCHEMBL7443144 | 0.84 | KDM1A (0.62) | NMUR2AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL30445757 | 0.84 | SLC6A2 (0.62) | CALCRLSLC6A2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962642-A | TREATING PROTEIN/PEPTIDE HAVING AMINO TERMINAL ACETYLATED AMINO ACID WITH ACID TO ACETYLATE HYDROXYL GROUP, TREATING WITH ISOTHIOCYANATE COMPOUND IN PRESENCE OF ACID TO FORM THIOCARBAMYL PROTEIN/PEPTIDE, ANALYSIS BY EDMAN DEGRADATION | SEIKO INSTRUMENTS INC. (JP) | 1999-10-05 | — | — | US | disclosed |