Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.34 |
| ▸ | CES2 | O00748 | 4/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502037 | 0.94 | CA1 (0.39) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL3500621 | 0.85 | — | — | |
| SCHEMBL11782359 | 0.79 | ZDHHC20 (0.32) | DNM1CES2CES1MEN1KMT2A | |
| Ethyl Nitrosourea SCHEMBL77485 | 0.75 | — | — | |
| SCHEMBL14938576 | 0.74 | EPHX1 (0.38) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL103667 | 0.74 | CA12 (0.40) | DNM1CES2CES1CA1CA12 | |
| SCHEMBL293960 | 0.73 | CA12 (0.48) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL103820 | 0.72 | CA12 (0.39) | CES2CES1CA1CA12CA9 | |
| SCHEMBL11179593 | 0.71 | — | — | |
| SCHEMBL87565 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856571-A | Semicarbazide-containing linker compounds for formation of stably-linked conjugates and methods related thereto | CELLPRO, INCORPORATED (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1996040263-A2 | SEMICARBAZIDE-CONTAINING LINKER COMPOUNDS FOR FORMATION OF STABLY-LINKED CONJUGATES AND METHODS RELATED THERETO | CELLPRO, INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |