Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567112 | 0.86 | TSHR (0.44) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL11651842 | 0.85 | MEN1 (0.50) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL11651847 | 0.85 | MEN1 (0.50) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL20258497 | 0.83 | TSHR (0.59) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL10035793 | 0.83 | TSHR (0.59) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL9657630 | 0.76 | TSHR (0.50) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL9657634 | 0.76 | TSHR (0.50) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL12990290 | 0.75 | MAPT (0.45) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL9611207 | 0.74 | POLB (0.48) | TSHRGAAGLAPOLBTDP1 | |
| SCHEMBL11648036 | 0.74 | POLB (0.48) | TSHRGAAGLAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856431-A | POLYIMIDE | ALLIANT TECHSYSTEMS INC. (US) | 1999-01-05 | — | — | US | disclosed |