Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035793 | 1.00 | TSHR (0.59) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL11651847 | 0.91 | MEN1 (0.50) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL9657630 | 0.91 | TSHR (0.50) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL11651842 | 0.91 | MEN1 (0.50) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL9657634 | 0.91 | TSHR (0.50) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL9611207 | 0.89 | POLB (0.48) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL11648036 | 0.89 | POLB (0.48) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL7567112 | 0.85 | TSHR (0.44) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL11647491 | 0.83 | TSHR (0.43) | TSHRGAAPOLBGLAKIF11 | |
| SCHEMBL8521396 | 0.83 | TSHR (0.43) | TSHRGAAPOLBGLAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163135-A1 | LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION | JNC CORPORATION (JP) | 2018-06-14 | — | — | US | disclosed |