Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.57 |
| ▸ | ACE | P12821 | 11/20 | 0.57 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017403 | 1.00 | MME (0.57) | MMEACEACACBKMT2AATM | |
| SCHEMBL27441338 | 0.96 | MME (0.52) | MMEACEACACBKMT2AATM | |
| SCHEMBL8028601 | 0.92 | MME (0.62) | MMEACEACACBKMT2AACACA | |
| SCHEMBL8028603 | 0.92 | MME (0.62) | MMEACEACACBKMT2AACACA | |
| SCHEMBL8452097 | 0.92 | MME (0.62) | MMEACEACACBKMT2AACACA | |
| SCHEMBL8454383 | 0.89 | MME (0.62) | MMEACEKMT2AATM | |
| SCHEMBL8030967 | 0.89 | MME (0.62) | MMEACEKMT2AATM | |
| SCHEMBL8452375 | 0.88 | MME (0.55) | MMEACEKMT2AATMPTGES | |
| SCHEMBL9007772 | 0.88 | MME (0.55) | MMEACEKMT2AATMPTGES | |
| SCHEMBL8026907 | 0.88 | MME (0.55) | MMEACEKMT2AATMPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |