Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.55 |
| ▸ | ACE | P12821 | 7/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007772 | 1.00 | MME (0.55) | MMEACECTSBATMCTSL | |
| SCHEMBL8026907 | 1.00 | MME (0.55) | MMEACECTSBATMCTSL | |
| SCHEMBL8028603 | 0.94 | MME (0.62) | MMEACECTSBPTGESMEN1 | |
| SCHEMBL8028601 | 0.94 | MME (0.62) | MMEACECTSBPTGESMEN1 | |
| SCHEMBL8452097 | 0.94 | MME (0.62) | MMEACECTSBPTGESMEN1 | |
| SCHEMBL8017403 | 0.88 | MME (0.57) | MMEACEATMPTGESKMT2A | |
| SCHEMBL8521824 | 0.88 | MME (0.57) | MMEACEATMPTGESKMT2A | |
| SCHEMBL8522441 | 0.86 | MME (0.54) | MMEACE | |
| SCHEMBL8033023 | 0.86 | MME (0.54) | MMEACE | |
| SCHEMBL8456166 | 0.86 | MME (0.61) | MMEACEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |