SCHEMBL852188

SCHEMBL852188

OP1(=S)Oc2ccccc2O1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.35
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
GPR84 Q9NQS5 3/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
LMNA P02545 2/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALOX5 P09917 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887329 0.90 KDM4E (0.34) GPR84
SCHEMBL28581470 0.84 BCHE (0.32) MAOA
SCHEMBL12830051 0.77 ABCG2 (0.35) ABCG2ITGB2ICAM1ITGALMAOA
SCHEMBL15044900 0.76 NISCH (0.35) MAOAMAOBLMNA
SCHEMBL29415555 0.71 GPR84 (0.57) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL9126685 0.71 ABCG2 (0.35) ABCG2ITGB2ICAM1ITGALMAOA
SCHEMBL5804639 0.71 GPR84 (0.57) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL930972 0.68 KDM4E (0.31)
SCHEMBL4103873 0.67 GPR84 (0.48) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL9124219 0.67 GPR84 (0.33) ABCG2ITGB2ICAM1ITGALGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2143331-B1 Fan type chemicals diffusing apparatus FUMAKILLA LTD (JP) 2018-06-20 EP disclosed
EP-2295440-B1 New ionic liquids based on thiophosphate anions and preparations thereof IFP ENERGIES NOW (FR) 2017-03-22 EP disclosed
EP-1356728-B1 FAN TYPE CHEMICAL DISPERSION EQUIPMENT FUMAKILLA LTD (JP) 2012-03-28 EP disclosed
EP-1262100-B1 FAN TYPE CHEMICALS DIFFUSING DEVICE FUMAKILLA LTD (JP) 2011-07-06 EP disclosed
EP-2295440-A1 New ionic liquids based on thiophosphate anions and preparations thereof IFP Energies nouvelles (FR) 2011-03-16 EP disclosed
EP-2143331-A2 Fan type chemicals diffusing apparatus Fumakilla Limited (JP) 2010-01-13 EP disclosed
EP-1356728-A1 FAN TYPE CHEMICAL DISPERSION EQUIPMENT Fumakilla Limited (JP) 2003-10-29 EP disclosed
EP-1262100-A1 FAN TYPE CHEMICALS DIFFUSING DEVICE Fumakilla Limited (JP) 2002-12-04 EP disclosed