Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951901 | 0.84 | MEN1 (0.54) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL11000436 | 0.82 | MEN1 (0.52) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL10957363 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL10996178 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL10911920 | 0.80 | MEN1 (0.50) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL10506374 | 0.77 | CYP19A1 (0.49) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL11199447 | 0.76 | MEN1 (0.45) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL9202578 | 0.76 | MEN1 (0.46) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL11359678 | 0.75 | POLB (0.46) | MEN1KMT2ATDP1CYP19A1HSP90AA1 | |
| SCHEMBL11365125 | 0.75 | POLB (0.61) | MEN1KMT2ATDP1CYP19A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272367-B1 | Synergistic insecticidal mixtures | BAYER CROPSCIENCE AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| EP-2272367-A1 | Synergistic insecticidal mixtures | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-7049271-B2 | Phenyl-substituted 2-enamino-ketonitriles | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-23 | — | — | US | disclosed |
| US-20060100106-A1 | Phenyl-substituted 2-enamino-ketonitriles | FISCHER REINER | 2006-05-11 | — | — | US | disclosed |
| EP-1129071-B1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER CROPSCIENCE AG (DE) | 2005-10-26 | — | — | EP | disclosed |
| US-20030220196-A1 | Phenyl-substituted-2enamino-keto nitriles | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100106-A1 | Phenyl-substituted 2-enamino-ketonitriles | AR, KCNK4, KCNA1 | MEN1 4347/4885KMT2A 244/4885TDP1 2937/4885 |
| US-20030220196-A1 | Phenyl-substituted-2enamino-keto nitriles | CYP1A1, CYP4X1, KCNK4 | MEN1 4281/4885KMT2A 452/4885TDP1 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.