Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442272 | 0.88 | BCHE (0.43) | BCHEGPR119 | |
| SCHEMBL7321256 | 0.83 | NOTUM (0.60) | NOTUMNPC1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7311635 | 0.83 | NOTUM (0.60) | NOTUMNPC1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL927332 | 0.81 | ACE (0.55) | — | |
| SCHEMBL705456 | 0.81 | ACE (0.55) | — | |
| SCHEMBL29443087 | 0.81 | ACE (0.55) | — | |
| SCHEMBL31092820 | 0.81 | ACE (0.55) | — | |
| SCHEMBL3702462 | 0.81 | ACE (0.55) | — | |
| SCHEMBL29545684 | 0.81 | ACE (0.55) | — | |
| SCHEMBL13108813 | 0.80 | NOTUM (0.65) | NOTUMNPC1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896580-A1 | SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS | ASTA Medica Aktiengesellschaft (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997041148-A1 | SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |