Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755875 | 0.81 | HIF1A (0.59) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL5073353 | 0.80 | HIF1A (0.55) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL7339589 | 0.80 | MEN1 (0.57) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL12846060 | 0.76 | HIF1A (0.64) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL424285 | 0.76 | HIF1A (0.59) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL2755865 | 0.76 | KDM4E (0.62) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL12783382 | 0.75 | HIF1A (0.55) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL7974997 | 0.75 | HIF1A (0.58) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL424284 | 0.75 | HIF1A (0.58) | KMT2AMEN1HIF1AKDM4ETDP1 | |
| SCHEMBL7974996 | 0.75 | HIF1A (0.58) | KMT2AMEN1HIF1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901373-A4 | Alpha v Beta 3 ANTAGONISTS | MERCK & CO INC (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0901373-A1 | Alpha v Beta 3 ANTAGONISTS | Merck & Co., Inc. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997037655-A1 | αvβ3 ANTAGONISTS | MERCK & CO., INC. (US) | 1997-10-16 | — | — | WO | disclosed |