Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.75 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522124 | 1.00 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8466113 | 1.00 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8466117 | 1.00 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8466111 | 1.00 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8464095 | 0.94 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8465979 | 0.94 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8465774 | 0.94 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8465780 | 0.94 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8465632 | 0.94 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8829477 | 0.88 | LTB4R (0.71) | LTB4RLTB4R2CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998451-A | LIPOXYGENASE INHIBITORS | PFIZER INC (US) | 1999-12-07 | — | — | US | disclosed |