Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.75 |
| ▸ | ACE | P12821 | 13/20 | 0.75 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027418 | 1.00 | MME (0.75) | MMEACELPAR1LPAR5CPA1 | |
| SCHEMBL27461895 | 0.95 | MME (0.67) | MMEACELPAR1LPAR5CPA1 | |
| SCHEMBL8030959 | 0.94 | MME (0.76) | MMEACELPAR1CPA1ACE2 | |
| SCHEMBL8027628 | 0.93 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL8521900 | 0.93 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL27464502 | 0.92 | MME (0.63) | MMEACELPAR1LPAR5TACR1 | |
| SCHEMBL27446787 | 0.91 | MME (0.63) | MMEACELPAR1LPAR5TACR1 | |
| SCHEMBL8028028 | 0.90 | MME (0.64) | MMEACELPAR1LPAR5 | |
| SCHEMBL8028033 | 0.90 | MME (0.64) | MMEACELPAR1LPAR5 | |
| SCHEMBL8448735 | 0.90 | MME (0.64) | MMEACELPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |