Styrene

Styrene

SCHEMBL8522148

C=CC#N.C=CC(=O)OC.C=CC=CC=Cc1ccccc1.C=CCOC(=O)C(=C)C.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
MAPT P10636 4/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 5/20 0.36
ALOX12 P18054 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
RECQL P46063 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL16395646 0.85 MAPT (0.44) LMNAMAPTKDM4EMEN1GAA
Styrene SCHEMBL3214945 0.85 MAPT (0.41) LMNAMAPTKDM4EMEN1GAA
Styrene SCHEMBL2892053 0.84 MAPT (0.44) LMNAMAPTKDM4EMEN1GAA
SCHEMBL87755 0.84 LMNA (0.47) LMNAMAPTKDM4EMEN1GAA
SCHEMBL10747808 0.83 LMNA (0.42) LMNAMAPTKDM4EMEN1GAA
SCHEMBL6408239 0.82 MAPT (0.41) LMNAMAPTKDM4EMEN1GAA
SCHEMBL11872611 0.82 MAPT (0.44) LMNAMAPTKDM4EMEN1GAA
Acrylonitrile SCHEMBL9631539 0.82 LMNA (0.41) LMNAMAPTKDM4EALDH1A1SMN1; SMN2
Styrene SCHEMBL9359631 0.82 LMNA (0.38) LMNAMAPTKDM4EMEN1GAA
Styrene SCHEMBL5460311 0.79 MAPT (0.42) LMNAMAPTKDM4EMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5871670-A Electroconductive composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-16 US disclosed
EP-0512951-B1 Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers CIBA GEIGY AG (CH) 1997-07-23 EP disclosed
EP-0782750-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION Ciba SC Holding AG (CH) 1997-07-09 EP disclosed
EP-0517658-B1 Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione CIBA GEIGY AG (CH) 1997-01-29 EP disclosed
EP-0491659-B1 Novel piperidine compounds containing silane groups for use as stabilizers for organic materials CIBA GEIGY AG (CH) 1997-01-22 EP disclosed
US-5578665-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
EP-0517659-B1 Novel piperidine compounds containing a tetrahydrofuran ring for use as stabilisers for organic materials CIBA GEIGY AG (CH) 1996-09-18 EP disclosed
EP-0512948-B1 Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
WO-1996009629-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION CIBA SPECIALTY CHEMICALS HOLDIING INC (CH) 1996-03-28 WO disclosed
US-5492652-A Dithiopentacene derivatives, their preparation and the use thereof as electron acceptors in charge transfer complexes CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
US-5185445-A Absorbers of ultraviolet radiation; stabilizers for organic polymers CIBA-GEIGY CORPORATION (US) 1993-02-09 US disclosed
EP-0523007-A1 Novel tetramethylpiperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1993-01-13 EP disclosed
EP-0521820-A1 2,6-Diarylpiperidin-1-yl substituted 2-butene stabilizers CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
EP-0518807-A1 Piperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1992-12-16 EP disclosed
EP-0517658-A1 Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
EP-0517659-A1 Novel piperidine compounds containing a tetrahydrofuran ring for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
EP-0512948-A1 Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
EP-0512951-A1 Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
EP-0491659-A2 Novel piperidine compounds containing silane groups for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1992-06-24 EP disclosed
EP-0479724-A2 Piperidine-triazine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1992-04-08 EP disclosed